A sustainable pediatric liver transplant program requires a comprehensive approach – early diagnosis, timely referral, and coordination between the private and public healthcare sectors. Many countries in Asia and Africa with limited resources do not have these structures in place. The lack of economic development in developing countries is a crucial hurdle to access LT. Managing malnutrition and infectious diseases are given due precedence over transplantation and therefore, LT remains largely unavailable in the public sector. With the absence of universal insurance cover, the onus of funding is largely on the family. Need for regular follow- up and cost of immunosuppression add to the economic drain.
About 3 decades after its inception in the West, the first successful pediatric liver transplant in India was performed at Apollo Hospitals, New Delhi in November 1998. Overcoming the hurdles of financial constraints, reservations about organ donation and donor safety in a largely living related program, India is now amongst the leading centers for LT in Asia. Between 1500-2000 transplants a year are performed, 10% of which are pediatric. Survival rates surpassing 90% have been achieved. The Apollo Liver Transplant Program has now performed more than 4000 liver transplants in patients from 50 countries. Of these 456 are pediatric transplants. The recipient of the first successful pediatric liver transplant in India, Sanjay then a twenty two month old baby is now working as a doctor in Bangalore. Children from 20 countries have received a transplant in our center.
Over the years, indications and donor pool have expanded. Age, size and now cost is no longer a barrier for successful LT. Babies weighing as little as 3.5 kg have received a successful transplant, Combined liver kidney transplants and ABO incompatible liver transplants are routinely performed. The average cost is 30,000 USD which is about one-fifth to one-tenth the cost in the West. Crowd funding along with the support of some philanthropic organizations and individuals dedicated to funding LT has thus made transplantation possible for those with limited resources. With increasing acceptance of LT among the medical community and the public at large, LT is now well established.