The development of IBD is known to be caused by environmental factors in hosts with a genetic predisposition. Changes in environmental factors are thought to be important factors in the development and prognosis of IBD compared to unchanging genetic factors. It has been reported that the incidence of IBD in Asian countries, including South Korea, is continuously increasing. The research of epidemiology in this region may be an important to find the factors of incidence and clinical outcomes of IBD in this region. As a source of bigdata, you can use the multi-hospital common data model or the public health data (PHD) provided by each country. PHD can provide the whole population depending on the supplied data from government and has the advantage of providing real world data in the study of such a rare disease as IBD. However, most of them are insurance claims data, which require an operational definition for accurate diagnosis, processing of data provided in code for anonymity, and statistical processing, which requires a multidisciplinary team approach. I would like to lecture on research using bigdata based on my personal research experience
To perform ERCP in children, there must first be data on the safety of the procedure. However, the current situation is that there is a lack of data on this topics. We expect the data from PEDI, a multi-center database comprised of 15 centers of patients less than 19 years old undergoing ERCP from May 2014 to May 2018, can provide answers to these questions partly in the future. The results of acute AE in pediatric ERCP to date have been reported similar to adults, according to meta analyses and a recent PEDI report. However, most ERCP procedures are accompanied by sphincterotomy, and there are no long-term reports of this. In our retrospective analysis, the incidence of gallstones, cholangitis, and biliary tract cancer was reported to be not high, demonstrating the long-term safety of the procedure. In children, the incidence of gallstones and hepatobiliary tract cancer is significantly lower than in adults, so number of ERCP in children is limited. However, due to the inability to diagnose with MRCP, the therapeutic aspect of being able to replace surgery, and the ability to perform biopsy, ERCP is an essential endoscopic procedure in children. In this lecture, based on the current data, I will lecture on the safety of pediatric ERCP and the indications for the procedure through the experience of the procedure.